LIN: Forschungsabteilungen > Akkustik, Lernen, Sprache > Unterpunkt Ebene 3 > Unterpunkt Ebene 4
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Projektleiter: Dr. rer. nat. Eike Budinger, Dr. med. Jürgen Goldschmidt
Zusammenarbeit innerhalb des IfN:Abtlg. Akustik, Lernen, Sprache Zusammenarbeit außerhalb des IfN:Universität Bochum // Biopsychologie Unterstützung:BMBF, CBBS, DAAD, DFG (SFB TRR31), LSA, WGL. Projektbeschreibung:Wir untersuchen hauptsächlich die funktionelle Organisation des auditorischen Kortex und dessen plastische Veränderungen, insbesondere während bestimmter Lernvorgänge. In diesem Zusammenhang entwickeln wir neue anatomische Methoden, die es uns u.a. ermöglichen, einen tieferen Einblick in die Funktionsweise des kortikalen Netzwerkes unter normalen, pathologischen und genmanipulierten Bedingungen zu gewinnen. Unsere Experimentalspezies sind:
Spezifisch untersuchen wir:
Hauptsächlich angewandte Methoden sind:
Wichtige Veröffentlichungen2010Goldschmidt, J., Wanger, T., Engelhorn, A., Friedrich, H., Happel, M., Ilango, A., Engelmann, M., Stuermer, I.W., Ohl, F.W., & Scheich H. (2010) High-resolution mapping of neuronal activity using the lipophilic thallium chelate complex TlDDC: protocol and validation of the method. Neuroimage 49, 303-315. 2009 Budinger, E., & Scheich, H. (2009) Anatomical connections suitable for the direct processing of neuronal information of different modalities via the rodent primary auditory cortex. Hear. Res. 258, 16-27. Macharadze, T., Goldschmidt, J., Marunde, M., Wanger, T., Scheich, H., Zuschratter, W., Gundelfinger, E.D., & Kreutz, M.R. (2009) Interretinal transduction of injury signals after unilateral optic nerve crush. Neuroreport 20, 301-305. 2008 Budinger, E., Laszcz, A., Lison, H., Scheich, H., & Ohl, F.W. (2008) Non-sensory cortical and subcortical connections of the primary auditory cortex in Mongolian gerbils: Bottom-up and top-down processing of neuronal information via field AI. Brain Res. 1220, 2-32. Jeschke, M., Lenz, D., Budinger, E., Herrmann, C.S., & Ohl, F.W. (2008) Gamma oscillations in gerbil auditory cortex during a target-discrimination task reflect matches with short-term memory. Brain Res. 1220, 70-80. Kurt, S., Deutscher, A., Crook, J.M., Ohl, F.W., Budinger, E., Scheich, H., & Schulze, H. (2008) Auditory cortical contrast enhancing inhibition acts globally rather than locally: Evidence for a neuronal implementation of a winner-take-all algorithm. PLOS One 3, e1735. Schicknick, H., Schott, B.H., Budinger, E., Smalla, K.-H., Riedel, A., Seidenbecher, C.I., Scheich, H., Gundelfinger, E.D., & Tischmeyer, W. (2008) Dopaminergic modulation of auditory cortex-dependent memory consolidation through mTOR. Cereb Cortex 18, 2646-2658. 2007 Angenstein, F., Niessen, H.G., Goldschmidt, J., Lison, H., Altrock, W.D., Gundelfinger, E.D., & Scheich, H. (2007) Manganese-enhanced MRI reveals structural and functional changes in the cortex of Bassoon mutant mice. Cereb. Cortex 17, 28-36. Scheich, H., Brechmann, A., Brosch, M., Budinger, E., & Ohl, F.W. (2007) The Cognitive Auditory Cortex: Task-Specificity of Stimulus Representations. Hear. Res. 229, 213-224. 2006 Bernstein, H.G., Lendeckel, U., Bertram, I., Bukowska, A., Kanakis, D., Dobrowolny, H., Stauch, R., Krell, D., Mawrin, C., Budinger, E., Keilhoff, G., & Bogerts, B. (2006) Localization of neuregulin-1alpha (heregulin-alpha) and one of its receptors, ErbB-4 tyrosine kinase, in developing and adult human brain. Brain Res. Bull. 69, 546-559. Budinger, E., Heil, P., Hess, A., & Scheich, H. (2006) Multisensory processing via early cortical stages: Connections of the primary auditory field with other sensory systems. Neurosci. 143, 1065-1083. Deutscher, A., Niessen, H.G., Angenstein, F., Goldschmidt, J., Scheich, H., & Schulze, H. (2006) Comparison of estimates for volumes of brain ablations derived from structural MRI and classical histology. J. Neurosci. Methods 156, 136-139. 2005 Budinger, E., & Heil, P. (2005) Anatomy of the auditory cortex. In: Greenberg, S., & Ainsworth, W. (eds.), Listening to speech, Lawrence Erlbaum Press, New Jersey, USA, pp. 91-113. Budinger, E (2005) Auditory cortical fields and their functions. In: König, R., Heil, P., Budinger, E., & Scheich, H. (eds.), The auditory cortex. A synthesis of human and animal research. Lawrence Earlbaum Press, New Jersey, USA, pp. 3-6. 2004 Angenstein, F., Niessen, H.G., Goldschmidt, J., Vielhaber, S., Ludolph, A.C., & Scheich, H. (2004) Age-dependent changes in MRI of motor brain stem nuclei in a mouse model of ALS. Neuroreport 15, 2271-2274. Goldschmidt, J., Zuschratter, W., & Scheich, H. (2004) High-resolution mapping of neuronal activity by thallium autometallography. Neuroimage 23, 638-647. 2002 Brosch, M., Budinger, E., & Scheich, H. (2002) Stimulus-related gamma-oscillations in primate auditory cortex. J. Neurophysiol. 87: 2715-2725. 2000 Budinger, E., Heil, P., & Scheich, H. (2000a) Functional organization of auditory cortex in the Mongolian gerbil (Meriones unguiculatus). III. Anatomical subdivisions and corticocortical connections. Eur. J. Neurosci. 12, 2425-2451. Budinger, E., Heil, P., & Scheich, H. (2000b) Functional organization of auditory cortex in the Mongolian gerbil (Meriones unguiculatus). IV. Connections with anatomically characterized subcortical structures. Eur. J. Neurosci. 12, 2452-2474. | |||
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